Research on technological process for producing live attenuated oral rotavirus vaccine for diarrhea prevention in Vietnam

PROJECT OVERVIEW

Project 'Technology for live attenuated oral Rota vaccine production' (KC.10.03/06-10) was conducted from 2007-2008 at POLYVAC.

Research Details
  • TOPIC NAME Research on technological process for producing live attenuated oral rotavirus vaccine for diarrhea prevention in Vietnam
  • Name of the principal Assoc. Prof. Dr. Lê Thị Luân
  • Classification State-level scientific research project
  • Execution time 2007-2008

Project/Topic Results

Procedures and Products
  • Procedures for creating master seed strains, working seed strains, and Rota virus vaccines
  • Testing procedures for master seed strains, working seed strains, and Rota virus vaccines
  • 2 master seed lots (MS), 5 working seed lots (WS), and 10,000 doses of Rota vaccine
  • Base standards based on World Health Organization guidelines
Human Resource Training
  • 01 Master
  • 01 PhD
  • 02 staff trained at CDC – USA
  • 05 staff trained in Rota vaccine production technology
  • 05 staff trained in Rota vaccine testing
Scientific Publications
  • 10 papers published in the Journal of Preventive Medicine
  • 01 Book: 'Rotavirus – Characteristics and Preventive Measures' – Medical Publishing House
  • 01 Patent: 'Procedure for production and master seed strain of Rota vaccine virus'